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1

A European perspective on the market accessibility of biosimilars

Declerck, Paul, Simoens, Steven

Journal:

Year:

2012

Language:

english

File:

PDF, 209 KB

english, 2012

2

Individual differences in behavioral flexibility in a probabilistic reversal learning task: An fMRI study.

Waegeman, Anja, Declerck, Carolyn H., Boone, Christophe, Seurinck, Ruth, Parizel, Paul M.

Journal:

Journal of Neuroscience, Psychology, and Economics

Year:

2014

Language:

english

File:

PDF, 4.00 MB

english, 2014

3

Neutrophil chemotaxis, phagocytosis, and superoxide release in depressive illness

Michael Maes, Wim Stevens, Luc DeClerck, Dirk Peeters, Chris Bridts, Chris Schote, Herbert Meltzer, Simon Scharpé, Paul Cosyns

Journal:

Biological Psychiatry

Year:

1992

Language:

english

File:

PDF, 474 KB

english, 1992

4

Biosimilars: controversies as illustrated by rhGH

Declerck, Paul J., Darendeliler, Feyza, Góth, Miklós, Kolouskova, Stanislava, Micle, Ioana, Noordam, Cees, Peterkova, Valentina, Volevodz, Natalia N., Zapletalová, Jiřina, Ranke, Michael B.

Journal:

Current Medical Research and Opinion

Year:

2010

Language:

english

File:

PDF, 226 KB

english, 2010

5

The Occurrence of Thrombosis in Inflammatory Bowel Disease Is Reflected in the Clot Lysis Profile

Bollen, Lize, Vande Casteele, Niels, Peeters, Miet, Van Assche, Gert, Ferrante, Marc, Van Moerkercke, Wouter, Declerck, Paul, Vermeire, Séverine, Gils, Ann

Journal:

Inflammatory Bowel Diseases

Year:

2015

Language:

english

File:

PDF, 432 KB

english, 2015

6

A fatal case of inappropriate adh secretion induced by cyclophosphamide therapy

Paul J. Harlow, Yves A. Declerck, Nomie A. Shore, Jorge A. Ortega, Alfonso Carranza, Eva Heuser

Journal:

Year:

1979

Language:

english

File:

PDF, 665 KB

english, 1979

7

Outcome after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis

Marc Ferrante, Sarah Declerck, Gert De Hertogh, Gert Van Assche, Karel Geboes, Paul Rutgeerts, Freddy Penninckx, Séverine Vermeire, Andre D'Hoore

Journal:

Inflammatory Bowel Diseases

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

8

Reciprocal regulation of tissue-type and urokinase-type plasminogen activators in the differentiation of murine preadipocyte line 3T3-L1 and the hormonal regulation of fibrinolytic factors in the mature adipocytes

Taiichiro Seki, Dr. Tomoko Miyasu, Toshinori Noguchi, Ayumi Hamasaki, Rika Sasaki, Yukiko Ozawa, Kaoru Okukita, Paul J. Declerck, Toyohiko Ariga

Journal:

Journal of Cellular Physiology

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

9

Plant pectin methylesterase and its inhibitor from kiwi fruit: Interaction analysis by surface plasmon resonance

Ruben P. Jolie, Thomas Duvetter, Ken Houben, Evelien Vandevenne, Ann M. Van Loey, Paul J. Declerck, Marc E. Hendrickx, Ann Gils

Journal:

Year:

2010

Language:

english

File:

PDF, 1004 KB

english, 2010

10

Activation of both coagulation and fibrinolysis in childhood hemolytic uremic syndrome

Van Geet, Chris, Proesmans, Willem, Arnout, Jef, Vermylen, Jos, Declerck, Paul J.

Journal:

Kidney International

Year:

1998

Language:

english

File:

PDF, 192 KB

english, 1998

11

Advances in understanding pectin methylesterase inhibitor in kiwi fruit: an immunological approach

Evelien Vandevenne, Stefanie Christiaens, Sandy Van Buggenhout, Ruben P. Jolie, Margarita González-Vallinas, Thomas Duvetter, Paul J. Declerck, Marc E. Hendrickx, Ann Gils, Ann Van Loey

Journal:

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

12

Effect of Reteplase™and PAI-1 antibodies on postoperative adhesion formation in a laparoscopic mouse model

Maria Mercedes Binda, Bart W. J. Hellebrekers, Paul J. Declerck, Philippe Robert Koninckx

Journal:

Surgical Endoscopy

Year:

2009

Language:

english

File:

PDF, 294 KB

english, 2009

13

Influence of interface charge inhomogeneities on the measurement of surface state densities in SiSiO2 interfaces by means of the MOS a.c. conductance technique

Paul A. Muls, Gilbert J. Declerck, Roger J. van Overstraeten

Journal:

Solid-State Electronics

Year:

1977

Language:

english

File:

PDF, 1.12 MB

english, 1977

14

His374 of wheat endoxylanase inhibitor TAXI-I stabilizes complex formation with glycoside hydrolase family 11 endoxylanases

Katleen Fierens, Ann Gils, Stefaan Sansen, Kristof Brijs, Christophe M. Courtin, Paul J. Declerck, Camiel J. De Ranter, Kurt Gebruers, Anja Rabijns, Johan Robben, Steven Van Campenhout, Guido Volckaer

Journal:

Year:

2005

Language:

english

File:

PDF, 416 KB

english, 2005

15

Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1

Aertgeerts, Kathleen, De Bondt, Hendrik L., De Ranter, Camiel J., Declerck, Paul J.

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 1.16 MB

1995

16

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

Bajou, Khalid, Maillard, Catherine, Jost, Maud, Lijnen, Roger H, Gils, Ann, Declerck, Paul, Carmeliet, Peter, Foidart, Jean-Michel, Noel, Agnès

Journal:

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

17

Extending the capabilities of targeted molecular dynamics: Simulation of a large conformational transition in plasminogen activator inhibitor 1

Peter Krüger, Stefan Verheyden, Paul J. Declerck, Yves Engelborghs

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 501 KB

english, 2001

18

Dynamic structural and functional relationships in recombinant plasminogen activator inhibitor-1 (rPAI-1)

Douglas E. Vaughan, Paul J. Declerck, Thomas M. Reilly, Kyusung Park, Désiré Collen, Gerald D. Fasman

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 823 KB

english, 1993

19

Comparison of random and oriented immobilisation of antibody fragments on mixed self-assembled monolayers

Kristien Bonroy, Filip Frederix, Gunter Reekmans, Ellen Dewolf, Randy De Palma, Gustaaf Borghs, Paul Declerck, Bruno Goddeeris

Journal:

Journal of Immunological Methods

Year:

2006

Language:

english

File:

PDF, 449 KB

english, 2006

20

Development and evaluation of monoclonal antibodies as probes to assess the differences between two tomato pectin methylesterase isoenzymes

Evelien Vandevenne, Sandy Van Buggenhout, Thomas Duvetter, Els Brouwers, Paul J. Declerck, Marc E. Hendrickx, Ann Van Loey, Ann Gils

Journal:

Journal of Immunological Methods

Year:

2009

Language:

english

File:

PDF, 468 KB

english, 2009

21

Study of Recombinant Antibody Fragments and PAI-1 Complexes Combining Protein-Protein Docking and Results from Site-Directed Mutagenesis

Hector Novoa de Armas, Maarten Dewilde, Koen Verbeke, Marc De Maeyer, Paul J. Declerck

Journal:

Year:

2007

Language:

english

File:

PDF, 33 KB

english, 2007

22

Study of Recombinant Antibody Fragments and PAI-1 Complexes Combining Protein-Protein Docking and Results from Site-Directed Mutagenesis

Hector Novoa de Armas, Maarten Dewilde, Koen Verbeke, Marc De Maeyer, Paul J. Declerck

Journal:

Year:

2007

Language:

english

File:

PDF, 866 KB

english, 2007

23

Neutralization of plasminogen activator inhibitor-1 inhibitory properties: identification of two different mechanisms

Sophie Debrock, Paul J Declerck

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1997

Language:

english

File:

PDF, 285 KB

english, 1997

24

Characterization of plasminogen activator inhibitor 1 mutants containing the P13 to P10 region of ovalbumin or antithrombin III: evidence that the P13 residue contributes significantly to the active to substrate transition

Ann Gils, Nele Vleugels, Kristof Tobback, Isabelle Knockaert, Paul J. Declerck

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1998

Language:

english

File:

PDF, 205 KB

english, 1998

25

The importance of helix F in plasminogen activator inhibitor-1

Nele Vleugels, Ann Gils, Ann-Pascale Bijnens, Isabelle Knockaert, Paul J. Declerck

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2000

Language:

english

File:

PDF, 203 KB

english, 2000

26

4 Pathophysiology of fibrinolysis

Irene Juhan-Vague, Marie-Christine Alessi, Paul J. Declerck

Journal:

Baillière's Clinical Haematology

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

27

An echistatin-like Arg-Gly-Asp (RGD)-containing sequence in the heavy chain CDR3 of a murine monoclonal antibody that inhibits human platelet glycoprotein IIb/IIIa function

Hans Deckmyn, Patrick Stanssens, Bernard Hoet, Paul J. Declerck, Marc Lauwereys, Yannick Gansemans, Istvan Tornai, Jos Vermylen

Journal:

British Journal of Haematology

Year:

1994

Language:

english

File:

PDF, 880 KB

english, 1994

28

Purification and characterization of natural and recombinant human plasminogen activator inhibitor-1 (PAI-1)

Marie Christine ALESSI, Paul J. DECLERCK, Maria DE MOL, Luc NELLES, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 1.38 MB

english, 1988

29

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation

Herbert Nar, Margit Bauer, Jean-Marie Stassen, Dietmar Lang, Ann Gils, Paul J Declerck

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 829 KB

english, 2000

30

Rational Design of Complex Formation between Plasminogen Activator Inhibitor-1 and Its Target Proteinases

Kathleen Aertgeerts, Camiel J. De Ranter, Nuala A. Booth, Paul J. Declerck

Journal:

Journal of Structural Biology

Year:

1997

Language:

english

File:

PDF, 193 KB

english, 1997

31

Characterization of common neoantigenic epitopes generated in plasminogen activator inhibitor-1 after cleavage of the reactive center loop or after complex formation with various serine proteinases

Sophie Debrock, Paul J. Declerck

Journal:

Year:

1995

Language:

english

File:

PDF, 452 KB

english, 1995

32

Comparative analysis of the proteinase specificity in wild-type and stabilized plasminogen activator inhibitor-1: evidence for contribution of intramolecular flexibility

Bart De Taeye, Ann Gils, Nele Vleugels, Anja Rabijns, Paul J. Declerck

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 356 KB

english, 2004

33

Development of an immunological toolbox to detect endogenous and exogenous pectin methylesterase in plant-based food products

Evelien Vandevenne, Sandy Van Buggenhout, Miet Peeters, Griet Compernolle, Paul J. Declerck, Marc E. Hendrickx, Ann Van Loey, Ann Gils

Journal:

Food Research International

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

34

Activation of the Zymogen to Urokinase-Type Plasminogen Activator Is Associated with Increased Interdomain Flexibility

Manja A. Behrens, Kenneth A. Botkjaer, Sumit Goswami, Cristiano L.P. Oliveira, Jan K. Jensen, Christine R. Schar, Paul J. Declerck, Cynthia B. Peterson, Peter A. Andreasen, Jan Skov Pedersen

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

35

Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences

Maarten Dewilde, Britt Van De Craen, Griet Compernolle, Jeppe B. Madsen, Sergei Strelkov, Ann Gils, Paul J. Declerck

Journal:

Journal of Structural Biology

Year:

2010

Language:

english

File:

PDF, 477 KB

english, 2010

36

Redirection of the reaction between activated protein C and a serpin to the substrate pathway

Andrey A. Komissarov, Peter A. Andreasen, Paul J. Declerck, Yuichi Kamikubo, Aiwu Zhou, András Gruber

Journal:

Thrombosis Research

Year:

2008

Language:

english

File:

PDF, 345 KB

english, 2008

37

High thrombin activatable fibrinolysis inhibitor levels are associated with an increased risk of premature peripheral arterial disease

Emile L.E. de Bruijne, Ann Gils, Dingeman C. Rijken, Moniek P.M. de Maat, Ana H.C. Guimarães, Don Poldermans, Paul J. Declerck, Frank W.G. Leebeek

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

38

Characterization of a panel of monoclonal antibodies toward mouse PAI-1 that exert a significant profibrinolytic effect in vivo

Britt Van De Craen, Ilse Scroyen, Rana Abdelnabi, Els Brouwers, H. Roger Lijnen, Paul J. Declerck, Ann Gils

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 727 KB

english, 2011

39

Maximal PAI-1 inhibition in vivo requires neutralizing antibodies that recognize and inhibit glycosylated PAI-1

Britt Van De Craen, Ilse Scroyen, Christine Vranckx, Griet Compernolle, H. Roger Lijnen, Paul J. Declerck, Ann Gils

Journal:

Thrombosis Research

Year:

2012

Language:

english

File:

PDF, 468 KB

english, 2012

40

Enhanced expression of plasminogen activator inhibitor-1 by dedifferentiated thyrocytes

Grazyna Kotlarz, Yanusz Wegrowski, Laurent Martiny, Paul J Declerck, Georges Bellon

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 340 KB

english, 2002

41

Identification of positively charged residues contributing to the stability of plasminogen activator inhibitor 1

Ann Gils, Jie Lu, Kathleen Aertgeerts, Isabelle Knockaert, Paul J Declerck

Journal:

Year:

1997

Language:

english

File:

PDF, 584 KB

english, 1997

42

Identification of functional synergism between monoclonal antibodies. Application to the enhancement of plasminogen activator inhibitor-1 neutralizing effects

Thu-Hoa Ngo, Sophie Debrock, Paul J Declerck

Journal:

Year:

1997

Language:

english

File:

PDF, 485 KB

english, 1997

43

Cloning of a single-chain variable fragment (scFv) switching active plasminogen activator inhibitor-1 to substrate

Sophie Debrock, Luigi Sironi, Paul J Declerck

Journal:

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

44

Monoclonal antibodies: indications, budget impact and use

Steven Simoens, Thomas De Rijdt, Paul Declerck

Journal:

Journal of Pharmaceutical Health Services Research

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

45

The Biochemistry, Physiology and Pathological roles of PAI-1 and the requirements for PAI-1 inhibition in vivo

Van De Craen, Britt, Declerck, Paul J., Gils, Ann

Journal:

Thrombosis Research

Year:

2012

Language:

english

File:

PDF, 256 KB

english, 2012

46

Orthogonal 18F and 64Cu labelling of functionalised bis(thiosemicarbazonato) complexes

Carroll, Laurence, Bejot, Romain, Hueting, Rebekka, King, Robert, Bonnitcha, Paul, Bayly, Simon, Christlieb, Martin, Dilworth, Jonathan R., Gee, Antony D., Declerck, Jérôme, Gouverneur, Véronique

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

47

A study on the blunted natural killer cell activity in severely depressed patients

Michael Maes, Wim Stevens, Dirk Peeters, Luc DeClerck, Simon Scharpe, Chris Bridts, Chris Schotte, Paul Cosyns

Journal:

Year:

1992

Language:

english

File:

PDF, 577 KB

english, 1992

48

Tryptophan Properties in Fluorescence and Functional Stability of Plasminogen Activator Inhibitor 1

Verheyden, Stefan, Sillen, Alain, Gils, Ann, Declerck, Paul J., Engelborghs, Yves

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 288 KB

english, 2003

49

Interchanging lexical resources on the Semantic Web

John McCrae, Guadalupe Aguado-de-Cea, Paul Buitelaar, Philipp Cimiano, Thierry Declerck, Asunción Gómez-Pérez, Jorge Gracia, Laura Hollink, Elena Montiel-Ponsoda, Dennis Spohr, Tobias Wunner

Journal:

Language Resources and Evaluation

Year:

2012

Language:

english

File:

PDF, 677 KB

english, 2012

50

Immunological methods to study the fibrinolytic system

Paul J. Declerck

Journal:

Fibrinolysis and Proteolysis

Year:

1993

Language:

english

File:

PDF, 282 KB

english, 1993